Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement
Astrid Hoermann, Sofia Tapanelli, Paolo Capriotti, Giuseppe Del Corsano, Ellen K. G. Masters, Tibebu Habtewold, George K. Christophides, Nikolai Windbichler
This paper converts endogenous mosquito genes into non-autonomous gene drives for malaria control by using native regulatory sequences to express antimalarial molecules and guide-RNAs.
eLife · Apr 12, 2021Peer-reviewedSynthetic Biology