Elodie Pronier

The paper identifies non-covalent inhibitors of PRDX5, a protein upregulated in MPM, through a machine learning guided pipeline and biochemical validation, suggesting it as a therapeutic target.

This paper introduces MISO, a deep learning method that predicts spatial transcriptomics data from H&E slides, enabling spatially resolved gene expression and patient representation for downstream tasks.

The paper introduces a machine-learning method to identify recurrent cell-cell communication patterns across tumor samples using spatial transcriptomics and single-cell data, revealing key immune and genetic programs in bladder cancer.

The paper identifies a prognostic infiltration zone in glioblastoma using histology and spatial transcriptomic integration, revealing specific cell composition associated with long-term survival.

This study uses deep learning to predict YAP1/TEAD activity from histology slides, linking histological patterns to disease aggressiveness in cancer patients.

This paper introduces HE2RNA, a deep learning model that predicts RNA-Seq profiles from histology slides without expert annotation, showing improved performance in predicting microsatellite instability.