Interplay between T3SS effectors, ExoY activation, and cGMP signaling in Pseudomonas aeruginosa infection
Vincent Deruelle, Gabrielle Dupuis, Dorothée Raoux‐Barbot, Elysa Lim, Roberto Ponce-López, Magda Teixeira Nunes, Daniel Ladant, Louis Renault, Undine Mechold
The paper investigates how ExoY-catalyzed cGMP modulates ExoT cytotoxicity and reveals reciprocal interactions between T3SS effectors in P. aeruginosa infections.
Nature Communications · Dec 2, 2025Peer-reviewedMicrobiology