Type I interferon-driven lung pathology restricts T cell accumulation and motility during tuberculosis
Maxime Caouaille, Léa Fromont, Tomoyo Shinkawa, Marion Faucher, Aizat Iman Abdul Hamid, Annie Béhar, Serge Mazères, Yael Duverge, Emeline Decarpentrie, Yohan Lorreyte, Emmanuelle Näser, Samuel M. Behar, Emma Lefrançais, Olivier Neyrolles, Denis Hudrisier
This study shows that type I interferon signaling in tuberculosis restricts T cell accumulation and motility by altering lung pathology and T cell states.
bioRxiv · Jun 3, 2026 · PreprintImmunology