Serge Mazères

Type I interferon-driven lung pathology restricts T cell accumulation and motility during tuberculosis

This study shows that type I interferon signaling in tuberculosis restricts T cell accumulation and motility by altering lung pathology and T cell states.

Identification of a unique TUBB3+ cell population in the tuberculosis granuloma

The paper identifies a TUBB3+ cell population in TB granulomas across multiple species and patients, distinct from known cell types and present in other infections.

Glophyt: a user-friendly, general-purpose program for nonlinear and multidimensional curve fitting via a hybrid stochastic and deterministic approach

Glophyt is a program for nonlinear and multidimensional curve fitting using a hybrid stochastic and deterministic approach, enabling parameter extraction from complex data without prior parameter knowledge.

Mycobacteria-host interactions in human bronchiolar airway organoids

This study uses human airway organoids to model tuberculosis infection, showing mycobacteria infect epithelial cells with low efficiency and the organoid microenvironment controls but does not eliminate the pathogen.