SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
Liguo Zhang, Alexsia L. Richards, Andrew S. Khalil, Emile Wogram, Haiting Ma, Richard A. Young, Rudolf Jaenisch
SARS-CoV-2 RNA can be reverse-transcribed by LINE-1 or HIV-1 reverse transcriptase, integrated into the human genome, and transcribed as chimeric viral-cellular RNAs.
bioRxiv · Dec 12, 2020 · PreprintGenomics