Author

Haiting Ma

Whitehead Institute for Biomedical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Rudolf JaenischiD· 3 shared Richard A. YoungiD· 2 shared Alessandra Dall’AgneseiD· 1 shared Alexsia L. Richards· 1 shared Andrew S. KhaliliD· 1 shared Brian J. AbrahamiD· 1 shared Carrie M. Garrett-Engele· 1 shared Dongdong FuiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMolecular Biology

Rudolf JaenischORCID

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Author profile →

3 papers

Recent·Most cited

Multiplex genome editing of human pluripotent stem cells using Cpf1

Haiting Ma, Rudolf Jaenisch

This paper develops a Cpf1-based system for efficient multiplex genome editing in human pluripotent stem cells, achieving targeted knockin and knockout with minimal off-target effects.

BIO-PROTOCOL · Jan 1, 2024Peer-reviewedMolecular Biology

A nuclear receptor facilitates differentiation of human PSCs into more mature hepatocytes

Haiting Ma, Esmée de Zwaan, Yang Eric Guo, Paloma Cejas, Prathapan Thiru, Martijn van de Bunt, Jacob Fuglsbjerg Jeppesen, Sudeepa Syamala, Alessandra Dall’Agnese, Brian J. Abraham, Dongdong Fu, Carrie M. Garrett-Engele, Tony Lee, Henry W. Long, Linda Gay Griffith, , Rudolf Jaenisch

This study identifies thyroid hormone receptor THRB as a key regulator of hepatocyte maturation from human PSCs, showing that T3 treatment enhances gene expression and epigenetic features of mature hepatocytes.

bioRxiv · Mar 24, 2022 · PreprintDevelopmental Biology

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome

Liguo Zhang, Alexsia L. Richards, Andrew S. Khalil, Emile Wogram, Haiting Ma, Richard A. Young, Rudolf Jaenisch

SARS-CoV-2 RNA can be reverse-transcribed by LINE-1 or HIV-1 reverse transcriptase, integrated into the human genome, and transcribed as chimeric viral-cellular RNAs.

bioRxiv · Dec 12, 2020 · PreprintGenomics