Molecular BiologybioRxivPreprint
An SMN2 splicing-correcting antisense oligonucleotide promotes gene looping and transcription activation
José N. Stigliano, Emilia Haberfeld, Luciano E. Marasco…·Alberto Rodolfo Kornblihtt
The paper shows that an antisense oligonucleotide promotes gene looping and long-distance promoter activation through chromatin conformation changes.
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