Cancer BiologybioRxiv
Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia
Kyle Spinler, Michael Hamilton, Jeevisha Bajaj…·Tannishtha Reya
This study identifies MSI2-HOXA9 as a novel oncogenic translocation driving blast crisis in myeloid leukemia, showing increased aggressiveness and mitochondrial activation.
DOI 10.7554/elife.93645