Small siphophage binding to an open state of the LptDE outer membrane lipopolysaccharide translocon
Emily Dunbar, Robert Clark, Arnaud Baslé, Shenaz Allyjaun, Hector Newman, Julia Hubbard, Syma Khalid, Bert van den Berg
This paper identifies a novel open state of the LptDE translocon bound by a phage RBP, revealing potential for peptidomimetic inhibition and insights into phage resistance mechanisms.
Proceedings of the National Academy of Sciences · Nov 26, 2025Peer-reviewedMicrobiology