Endothelial c-Src mediates neovascular tuft formation in Oxygen-Induced Retinopathy
Emmanuelle Frampton, Priyanka Som, Brittany Hill, Alexander Yu, Marina Naval-Sanchez, Chistian M. Nefzger, Ivar Noordstra, Emma Gordon, Lilian Schimmel
This study shows that c-Src is essential for neovascular tuft formation in Oxygen-Induced Retinopathy, as its depletion reduces tuft formation without affecting cell death, proliferation, or adhesion.
bioRxiv · Apr 17, 2024Pathology