Ivar Noordstra

This study shows that c-Src is essential for neovascular tuft formation in Oxygen-Induced Retinopathy, as its depletion reduces tuft formation without affecting cell death, proliferation, or adhesion.

This study shows that an APC truncation mutant increases epithelial tissue tension via RhoA/ROCK, impairing apical cell extrusion and potentially contributing to disease.

The paper introduces a transgenic Lifeact-EGFP quail line for live imaging of actin dynamics during avian embryogenesis and demonstrates its utility in studying cellular protrusions and supracellular actin structures.