Deletion of endocannabinoid synthesizing enzyme DAGLα from cerebellar Purkinje cells decreases social preference and elevates anxiety
Gabriella Smith, Kathleen McCoy, Gonzalo Viana Di Prisco, Alexander Kuklish, Emma Grant, Mayil Bhat, Sachin Patel, Ken Mackie, Brady K. Atwood, Anna Kalinovsky
This study shows that deleting DAGLα in cerebellar Purkinje cells in mice leads to reduced social preference and increased anxiety.
bioRxiv · Aug 8, 2024 · PreprintNeuroscience