Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy.
Pablo Miguel Casillas-Espinosa, Alison Anderson, Anna Harutyunyan, Crystal N. Li, Ji-Yoon Lee, Emma L. Braine, Rhys D. Brady, Mujun Sun, Cheng Huang, Christopher K. Barlow, Anup D. Shah, Ralf B. Schittenhelm, Richelle Mychasiuk, Nigel C. Jones, Sandy R. Shultz, Terence John O'Brien
This study shows sodium selenate reduces seizures, cognitive dysfunction, and sensorimotor deficits in a rat model of chronic drug-resistant temporal lobe epilepsy.
eLife · Mar 9, 2023Peer-reviewedNeuroscience