Author

Pablo Miguel Casillas-Espinosa

Alfred HealthORCID 0000-0002-6199-9415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Terence John O'BrieniD· 3 shared Ali ShadiD· 2 shared Bridgette D. SempleiD· 2 shared Erskine Chu· 2 shared Jian LiiD· 2 shared Sarah S. J. RewelliD· 2 shared Alison AndersoniD· 1 shared Anna HarutyunyaniD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Terence John O'BrienORCID

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3 papers

Recent·Most cited

NeuroscienceEpilepsiaPeer-reviewedJul 15, 2025

Chronic Behavioral and Seizure Outcomes following Experimental Traumatic Brain Injury and Comorbid Klebsiella pneumoniae Lung Infection in Mice

Sarah S. J. Rewell, Ali Shad, L. Chen…·Bridgette D. Semple

This study investigates the long-term effects of Klebsiella pneumoniae infection following traumatic brain injury in mice, finding no significant impact on neurobehavioral outcomes or seizure development.

1 citation

mouseexperimental assay

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NeuroscienceExperimental NeurologyPeer-reviewedJan 20, 2025

A post-injury immune challenge with lipopolysaccharide following adult traumatic brain injury alters neuroinflammation and the gut microbiome acutely, but has little effect on chronic outcomes

Sarah S. J. Rewell, Ali Shad, Lingjun Chen…·Bridgette D. Semple

This study shows that LPS treatment after TBI causes acute neuroinflammation and gut microbiome changes but does not affect long-term outcomes.

7 citations

mousebulk RNA-seq

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NeuroscienceeLifePeer-reviewedMar 9, 2023

Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy.

Pablo Miguel Casillas-Espinosa, Alison Anderson, Anna Harutyunyan…·Terence John O'Brien

This study shows sodium selenate reduces seizures, cognitive dysfunction, and sensorimotor deficits in a rat model of chronic drug-resistant temporal lobe epilepsy.

37 citationstop 2%

ratproteomics

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