Ecological interactions in breast cancer: Cell facilitation promotes growth and survival under drug pressure
Rena Emond, Jason I. Griffiths, Vince Kornél Grolmusz, Aritro Nath, Jinfeng Chen, Eric F. Medina, Rachel S. Sousa, Frederick R. Adler, Andrea H. Bild
The paper shows that drug-sensitive breast cancer cells benefit from co-culture with resistant cells, which produce estradiol, leading to increased survival and resistance under treatment.
bioRxiv · Feb 1, 2021 · PreprintSystems Biology