Jinfeng Chen

The paper uses a phased genome of the Fairchild mandarin to analyze how haplotype-specific chromatin states influence allele-specific gene expression.

The paper shows that drug-sensitive breast cancer cells benefit from co-culture with resistant cells, which produce estradiol, leading to increased survival and resistance under treatment.

The paper reconstructs tumor size trajectories during therapy by integrating multiple measurement modalities to identify distinct patterns of tumor response and resistance.

Hapi infers chromosome-length haplotypes from 3-5 gametes, outperforming existing methods in accuracy, reliability, and cost efficiency.

The paper shows that combining ribociclib and adavosertib reduces growth of mixed cancer cell cultures and limits resistance development.

The paper tracks transposable element dynamics during rice domestication, identifying two key events that contributed to mPing hyperactivity.