BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate
Isabella M. Valentino, Jeniffer G. Llivicota-Guaman, Thuy Phuong Dao…·Daniel Adam Kraut
This study shows that polyubiquitinated substrates modulate UBQLN2 phase separation in a linkage-dependent manner, affecting proteasome activity and deubiquitination.
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