Thuy Phuong Dao

Mass spectrometric detection of protein nanoclusters: the invisible intermediates of phase separation

The paper uses charge detection mass spectrometry to detect protein nanoclusters, revealing their mass dispersion and polydispersity as intermediates in phase separation.

STI1 domains coordinate partitioning of UBQLN2 into stress-induced condensates

This study identifies distinct roles of STI1 domains in UBQLN2's phase separation and stress-induced condensate formation in human cells.

STI1 domain dynamically engages transient helices in disordered regions to drive self-association and phase separation of yeast ubiquilin Dsk2

This study identifies the STI1 domain's role in driving Dsk2 self-association and phase separation through interactions with transient helices in disordered regions, with implications for proteasome condensate formation.