Cellular and Immune Adaptations at the Maternal-Fetal Interface in Bats
Allyson Caldwell, Liheng Yang, Rebecca L. Casazza, Rizban E Worota, Cole R. McCutcheon, Patrick S. Creisher, Erika Zhan, Clara Reasoner, Ashley Higgins, Tony Schountz, Carolyn B. Coyne
This study uses single-nucleus RNA sequencing and organoids to identify unique placental cell types and immune adaptations in Jamaican fruit bats, revealing species-specific gene programs and attenuated antiviral responses in trophoblasts.
Cell Reports · Dec 1, 2025Peer-reviewedDevelopmental Biology