Author

Ernest Myguel Esteban

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexandrine MahoudeauiD· 1 shared B. Tendrel· 1 shared Heta Lad· 1 shared Manish Kumar SinghiD· 1 shared Olivier BenvénisteiD· 1 shared Penney M. GilbertiD· 1 shared Yekaterina TiperiD· 1 shared Yves AllenbachiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Alexandrine MahoudeauORCID

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1 paper

Recent·Most cited

BioengineeringSkeletal MusclePeer-reviewedNov 25, 2025

Distinct pathogenic influence of anti-HMGCR+ and anti-SRP+ immune-mediated necrotizing myopathy autoantibodies on engineered muscle function

Heta Lad, Yekaterina Tiper, Ernest Myguel Esteban…·Penney M. Gilbert

This study shows that anti-HMGCR and anti-SRP autoantibodies from IMNM patients have distinct direct effects on engineered muscle function, with anti-HMGCR reducing contractile force and anti-SRP causing atrophy without affecting force.

6 citations

humanexperimental assay

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