SPRINT-MS: A high-throughput platform for identifying protein-protein interactions using pooled IP-MS and sparse signal recovery.
Lena Annika Street, Moitrish Majumdar, Katherine L. Rothamel, Esin Gogus, Gloria Ann Brar, Gene Wei-Ming Yeo, Tomas Rube, Marko Jovanović
SPRINT-MS identifies protein-protein interactions using pooled IP-MS and sparse signal recovery, achieving high throughput and efficiency comparable to individual IP-MS experiments.
bioRxiv · Nov 21, 2025 · PreprintMolecular Biology