Lena Annika Street

This study shows that HP1β regulates olfactory receptor choice and neuronal identity in mice by modulating H3K9me3 levels and chromatin structure, leading to changes in OR expression patterns and reduced receptor diversity.

SPRINT-MS identifies protein-protein interactions using pooled IP-MS and sparse signal recovery, achieving high throughput and efficiency comparable to individual IP-MS experiments.

The paper constructs an RNA-aware RBP-centric PPI map across the mRNA life-cycle, revealing 20,359 novel interactions and showing 73% are RNA-dependent.

The paper develops a smFISH method with computational staging to study transcription dynamics in C. elegans embryos and finds that the DCC reduces dpy-23 transcription frequency.

The paper introduces SEC-MX, a method to simultaneously study protein assembly-states and phosphorylation events, and demonstrates its application in HEK293 and HCT116 cells.

The paper shows that condensin DC spreads from rex sites to form TADs on the X-chromosome in C. elegans, but not on autosomes unless rex sites are artificially added.

The paper shows that DCC binding reduces active histone modifications at X chromosome gene regulatory elements, fine-tuning X transcription.