Inhibition of GMP synthesis extends yeast replicative lifespan
Ethan A. Sarnoski, P. Liu, Guste Urbonaite, Tolga Tarkan Ölmez, Thomas Young, Ran Song, Murat Açar
This study shows that inhibiting GMP synthesis extends yeast replicative lifespan through a mechanism independent of known nutrient-sensing and sirtuin pathways.
bioRxiv · May 7, 2019 · PreprintSystems Biology