Author

Guste Urbonaite

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Murat AçariD· 2 shared Thomas Young· 2 shared Ethan A. Sarnoski· 1 shared P. Liu· 1 shared Ping LiuiD· 1 shared Ran SongiD· 1 shared Tolga Tarkan ÖlmeziD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersSystems Biology

Murat AçarORCID

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2 papers

Recent·Most cited

Quantitative insights into age-associated DNA-repair inefficiency in single cells

Thomas Young, Ping Liu, Guste Urbonaite, Murat Açar

The paper quantifies a 23.4% decline in single-strand annealing repair efficiency in old cells, linked to prolonged G1-phase duration and high heteroduplex rejection.

Cell Reports · Aug 1, 2019Peer-reviewedSystems Biology

Inhibition of GMP synthesis extends yeast replicative lifespan

Ethan A. Sarnoski, P. Liu, Guste Urbonaite, Tolga Tarkan Ölmez, Thomas Young, Ran Song, Murat Açar

This study shows that inhibiting GMP synthesis extends yeast replicative lifespan through a mechanism independent of known nutrient-sensing and sirtuin pathways.

bioRxiv · May 7, 2019 · PreprintSystems Biology