Two germ granule eIF4E isoforms reside in different mRNPs to hand off C elegans mRNAs from translational repression to activation
Gita Gajjar, Hayden P. Huggins, Eun Suk Kim, Weihua Huang, Frederic X. Bonnet, Dustin L. Updike, Brett D. Keiper
The paper identifies two eIF4E isoforms in C. elegans germ granules that regulate mRNA translation by sequentially repressing and activating germline mRNAs.
bioRxiv · May 24, 2024 · PreprintDevelopmental Biology