Frédéric Bonnet

Mesenchymal-derived neural progenitors underlie local insulin production and neuronal transdifferentiation during retina regeneration

This study identifies mesenchymal-derived neural progenitors that transdifferentiate into retinal ganglion cells in zebrafish after neuronal ablation, revealing a novel mechanism for retinal regeneration.

Zebrafish genetic model of neuromuscular degeneration associated with Atrogin-1 expression

The paper develops a zebrafish model of accelerated muscle atrophy by inducing Atrogin-1 expression, showing muscle degeneration, locomotion dysfunction, and neurodegenerative effects.

Two germ granule eIF4E isoforms reside in different mRNPs to hand off C elegans mRNAs from translational repression to activation

The paper identifies two eIF4E isoforms in C. elegans germ granules that regulate mRNA translation by sequentially repressing and activating germline mRNAs.

The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline

The paper identifies LOTR-1, a C. elegans protein with LOTUS and Tudor domains, which interacts with ZNFX-1 to regulate small RNA processing in the germline.

G1 PHASE LENGTHENING DURING NEURAL TISSUE DEVELOPMENT INVOLVES CDC25B INDUCED G1 HETEROGENEITY.

The paper measures cell cycle phases in neural progenitor cells and identifies CDC25B as an indirect regulator of G1 phase lengthening during tissue development.

Neurogenic decisions require a cell cycle independent function of the CD25B phosphatase

This study shows CDC25B phosphatase regulates neuronal production in the neural tube independently of cell cycle dynamics in chick neural progenitors.