Corticohippocampal circuit dysfunction in a mouse model of Dravet syndrome
Joanna Mattis, Ala Somarowthu, Kevin M. Goff, Evan Jiang, Jina Yom, Nathaniel P. Sotuyo, Laura M. McGarry, Huijie Feng, Keisuke Kaneko, Ethan M. Goldberg
This study identifies circuit dysfunction in the hippocampus of a Dravet syndrome mouse model and shows that restoring parvalbumin interneuron function can rescue circuit impairments.
eLife · Feb 25, 2022Peer-reviewedNeuroscience