Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
Kieran A. Boyle, Erika Polgár, María Gutièrrez‐Mecinas, Allen C. Dickie, Andrew H. Cooper, Andrew M. Bell, Evelline Jumolea, Adrián Casas-Benito, Masahiko Watanabe, David I. Hughes, Greg A. Weir, John S. Riddell, Andrew J. Todd
This study shows that NPY-expressing inhibitory interneurons in the spinal dorsal horn reduce pain and itch behaviors, suggesting they are potential targets for treating pathological pain and itch.
eLife · Mar 30, 2023Peer-reviewedNeuroscience