Late treatment initiation leads to reduced antiviral potency
Xuanlin Liu, Evelyn J. Franco, Sean N. Avedissian, Kaley C. Hanrahan, Jérémie Guedj, J. G. Coen van Hasselt, Ashley N. Brown, Anne‐Grete Märtson
This study shows that late antiviral treatment initiation reduces drug potency (EC50), and a time-varying EC50 model better fits viral load data than a constant EC50 model.
bioRxiv · Sep 24, 2025 · PreprintPharmacology & Toxicology