Jérémie Guedj

Modeling how memory CD8 T cells can elicit post-treatment control of HIV infection

This paper models how memory CD8 T cells can drive post-treatment control of HIV by analyzing SIV-infected non-human primate data and developing a mathematical framework.

The analysis of a large dataset of PCR-test results in the community reveals the impact of age, variants and vaccination status on SARS-CoV-2 viral dynamics

This study uses community PCR test data to estimate viral dynamics parameters and assess the impact of age, vaccination, and variants on SARS-CoV-2 infection.

Dynamics of interactions between three major respiratory pathogens in reconstituted human epithelium

This study examines virus-virus interactions among IAV, SARS-CoV-2, and RSV in a human airway epithelium model, revealing dynamic, asymmetric effects influenced by infection order and host responses.

Late treatment initiation leads to reduced antiviral potency

This study shows that late antiviral treatment initiation reduces drug potency (EC50), and a time-varying EC50 model better fits viral load data than a constant EC50 model.

Spatial dynamics of peripheral and central nervous system infection by an interferon-inducing neuroinvasive virus

This study examines how Sindbis virus spreads from peripheral to central nervous system in zebrafish, revealing distinct dynamics and the role of interferon responses.