Author

Anne‐Grete Märtson

Leiden UniversityORCID 0000-0001-6478-1959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

J. G. Coen van HasseltiD· 2 shared Xuanlin LiuiD· 2 shared Ashley N. BrowniD· 1 shared Dirk-Jan van den Berg· 1 shared Evelyn J. Franco· 1 shared Jérémie GuedjiD· 1 shared Jorn Brink· 1 shared Kaley C. Hanrahan· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. G. Coen van HasseltORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyAntimicrobial Agents and ChemotherapyPeer-reviewedJun 18, 2026

A Novel Hollow Fiber Infection Model (HFIM) for Antiviral PK/PD studies of CMV infection.

Lalitya M. Sudarsono, Suzanne A M Wenker, Xuanlin Liu…·Anne‐Grete Märtson

This paper introduces a novel hollow fiber infection model (HFIM) for PK/PD studies of ganciclovir in CMV infection, enabling reliable drug exposure and viral dynamics analysis.

3 citationstop 1%

humanexperimental assay

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Pharmacology & ToxicologybioRxivPreprintSep 24, 2025

Late treatment initiation leads to reduced antiviral potency

Xuanlin Liu, Evelyn J. Franco, Sean N. Avedissian…·Anne‐Grete Märtson

This study shows that late antiviral treatment initiation reduces drug potency (EC50), and a time-varying EC50 model better fits viral load data than a constant EC50 model.

DOI 10.1101/2025.09.24.678199

statistical modeldrug response / drug discovery

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