Molecular mechanisms of LC3-associated phagocytosis in the macrophage response to Paracoccidioides spp.
G. P. d. Oliveira, H. R. d. Sousa, K. C. d. M. Gorgonha, T. K. d. S. Borges, K. T. Rangel, S. Fabricant, F. C. K. Gustavo, L. F. F. Albuquerque, A. Rossi, F. A. Hurtado, H. C. Paes, A. Casadevall, I. Silva-Pereira, P. Albuquerque, M. S. S. Felipe, A. M. Nicola
This study investigates the role of LC3-associated phagocytosis in macrophage response to Paracoccidioides spp., finding that autophagy is important for antifungal activity and that signaling pathways differ from other fungi.
bioRxiv · Oct 30, 2020 · PreprintImmunology