Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer
R. I. Corona, J.-H. Seo, X. Lin, D. J. Hazelett, J. Reddy, F. Abassi, Y. G. Lin, P. Y. Mhawech-Fauceglia, J. Lester, S. P. Shah, D. G. Huntsman, A. Gusev, B. Y. Karlan, B. P. Berman, M. L. Freedman, , K. Lawrenson
The paper identifies histotype-specific regulatory elements in ovarian cancer by integrating chromatin landscapes and somatic mutations, highlighting the PAX8 pathway's role in tumor development.
bioRxiv · Feb 1, 2019Cancer Biology