Author

F. Bestvater

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Marchetto· 2 shared A. Narayanan· 2 shared B. Steffl· 2 shared C. Schmidt· 2 shared D. Krunic· 2 shared F. Cidre-Aranaz· 2 shared J. Li· 2 shared J. Musa· 2 shared

Activity by Year

2021-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

A. Marchetto

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

E. Demirdizen, R. Al-Ali, A. Narayanan, X. Sun, J. P. Varga, B. Steffl, M. Brom, D. Krunic, C. Schmidt, G. Schmidt, F. Bestvater, J. Taranda, S. Turcan

This study identifies TRIM67 as an oncogene in oligodendrogliomas that promotes cell motility, tumor growth, and membrane blebbing through Rho GTPase/ROCK signaling.

bioRxiv · Nov 5, 2021Cancer Biology

MEOX2 homeobox gene promotes growth of malignant gliomas

S. Turcan, A. Schönrock, E. Heinzelmann, B. Steffl, A. Narayanan, D. Krunic, M. Bähr, J.-W. Park, C. Schmidt, K. Ozduman, N. M. Pamir, W. Wick, F. Bestvater, D. Weichenhan, C. Plass, , M. Mall

This study identifies MEOX2 as an oncogenic transcription factor in glioblastoma, showing it promotes tumor growth through ERK signaling and cooperates with p53 and PTEN loss.

bioRxiv · Aug 24, 2021Cancer Biology

Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma

S. Ohmura, A. Marchetto, M. F. Orth, J. Li, S. Jabar, A. Ranft, E. Vinca, K. Ceranski, M. J. Carreno-Gonzalez, L. Romero-Perez, F. S. Wehweck, J. Musa, F. Bestvater, M. M. L. Knott, T. L. B. Hoelting, , T. G. P. Grunewald

This study identifies RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma, showing its overexpression correlates with poor survival and that its inhibition reduces tumor growth and overcomes chemoresistance.

bioRxiv · Mar 4, 2021Cancer Biology

Systems biology analysis identifies TCF7L1 as a key regulator of metastasis in Ewing sarcoma

F. Cidre-Aranaz, J. Li, T. L. B. Hoelting, M. F. Orth, R. Imle, S. Kutschmann, G. Ammirati, K. Ceranski, M. J. Carreno-Gonzalez, M. Kasan, A. Marchetto, C. M. Funk, F. Bestvater, S. Bersini, C. Arrigoni, , T. G. P. Gruenewald

bioRxiv · Feb 25, 2021 · PreprintCancer Biology