Author

F. Biscu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

B.-J. Ke· 3 shared G. Matteoli· 3 shared S. Abdurahiman· 3 shared S. Santhosh· 3 shared B. Verstockt· 2 shared J. Fric· 2 shared L. van Baarle· 2 shared M. Stakenborg· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

B.-J. Ke

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Unveiling the guardians: IL-26-expressing MAIT cells protect epithelial barrier function and are dysregulated in Crohn's disease

V. Bosakova, B.-J. Ke, M. Hortova Kohoutkova, I. Papatheodorou, F. Kafka, M. D. Zuani, S. Santhosh, F. Biscu, S. Abdurahiman, I. D. Greef, S. Verstockt, B. Verstockt, S. Vermeire, R. J. Arguello, G. Matteoli, J. Fric

This study identifies IL-26-expressing MAIT cells as protective for epithelial barrier function and shows their dysregulation in Crohn's disease.

bioRxiv · Jun 2, 2024 · PreprintImmunology

IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer

L. van Baarle, V. De Simone, L. Schneider, S. Santhosh, S. Abdurahiman, F. Biscu, R. Schneider, L. Zanoletti, S. Verbandt, Z. Hu, M. Stakenborg, B.-J. Ke, B. Garcia-Reyes, J. Henn, M. Toma, , G. Matteoli

This study identifies IL-1R signaling as a driver of enteric glia-macrophage interactions in colorectal cancer, promoting tumor progression through IL-6 secretion.

bioRxiv · Jun 1, 2023Cancer Biology

Intercellular interaction between FAP fibroblasts and CD150 inflammatory monocytes mediates fibro-stenosis in Crohn's disease

B.-J. Ke, S. Abdurahiman, F. Biscu, G. Dragoni, S. Santhosh, V. De Simone, A. Zouzaf, L. van Baarle, M. Stakenborg, V. Bosakova, Y. Van Rymenant, E. Verhulst, S. Verstockt, G. Bislenghi, A. Wolthuis, , G. Matteoli

The paper identifies intercellular interactions between FAP fibroblasts and CD150 monocytes that drive fibro-stenosis in Crohn's disease and shows TWIST1 inhibition can reduce fibrosis.

bioRxiv · May 4, 2023Immunology