Computational identification of small molecules for increased gene expression by synthetic circuits in mammalian cells
M. Pisani, F Calandra, Antonio Rinaldi, F. Cella, Francesca Tedeschi, Iolanda Boffa, Diego Vozzi, Nicola Brunetti‐Pierri, Annamaria Carissimo, Francesco Napolitano, Velia Siciliano
The paper identifies small molecules that enhance gene expression in synthetic circuits by analyzing RNA-seq data and drug-induced profiles.
Nature Communications · Aug 4, 2025Peer-reviewedSynthetic Biology