Author

Antonio Rinaldi

Italian Institute of TechnologyORCID 0000-0001-8854-6048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Velia SicilianoiD· 2 shared Annamaria CarissimoiD· 1 shared Assunta SellittoiD· 1 shared Daniela Perna· 1 shared Diego VozziiD· 1 shared Evangelos-Marios NikoladosiD· 1 shared F CalandraiD· 1 shared F. Cella· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Velia SicilianoORCID

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2 papers

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedAug 4, 2025

Computational identification of small molecules for increased gene expression by synthetic circuits in mammalian cells

M. Pisani, F Calandra, Antonio Rinaldi…·Velia Siciliano

The paper identifies small molecules that enhance gene expression in synthetic circuits by analyzing RNA-seq data and drug-induced profiles.

10 citations

humanbulk RNA-seq

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJan 9, 2025

Design of novel synthetic promoters to tune gene expression in T cells

Giuliano Bonfá, Giovanna Martino, Assunta Sellitto…·Velia Siciliano

The paper designs synthetic promoters that respond to TFs differentially expressed in activated and exhausted T cells, enabling functional state classification and dynamic gene expression control.

6 citations

humanCRISPR screen

𝕏 PostBluesky