Author

F. Colomb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Organism:non-human primate· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Jamwal· 3 shared A. Ogunkanbi· 2 shared H. J. McSorley· 2 shared M. K. Higgins· 2 shared A. R. Savage· 1 shared B. Dong· 1 shared C. A. Finney· 1 shared G. J. Wright· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

A. Jamwal

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3 papers

Recent·Most cited

Heparan sulphate binding controls in vivo half-life of the HpARI protein family

F. Colomb, A. Jamwal, A. Ogunkanbi, T. Frangova, A. R. Savage, S. Kelly, G. J. Wright, M. K. Higgins, H. J. McSorley

The paper shows that DNA and heparan sulphate binding prolongs the in vivo half-life of HpARI1 and HpARI2 proteins compared to HpARI3.

bioRxiv · May 6, 2024Immunology

IL-33-binding HpARI family homologues with divergent effects in suppressing or enhancing Type 2 immune responses

F. Colomb, A. Ogunkanbi, A. Jamwal, B. Dong, R. M. Maizels, C. A. Finney, J. D. Wasmuth, M. Higgins, H. McSorley

The paper identifies three HpARI family members in H. polygyrus bakeri, showing they have distinct effects on IL-33-dependent Type 2 immune responses.

bioRxiv · Oct 9, 2023Immunology

Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI

A. Jamwal, F. Colomb, H. J. McSorley, M. K. Higgins

The paper determines the structure of HpARI bound to mouse IL-33, showing how HpARI blocks IL-33 signaling by competing with its receptor ST2.

bioRxiv · Aug 10, 2023 · PreprintMicrobiology