MicrobiologybioRxiv
Novel Role of UHRF1 in DNA methylation-mediated repression of latent HIV-1
R. Verdikt, S. Bouchat, A. O. Pasternak…·C. Van Lint
This study identifies UHRF1 as a novel mediator of HIV-1 latency through DNA methylation and shows its inhibition reactivates latent HIV-1 in patient cells.
DOI 10.1016/j.ebiom.2022.103985