Author

F. Ismail-Beigi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

B. Dhayalan· 2 shared M. A. Weiss· 2 shared Y.-S. Chen· 2 shared D. Chatterjee· 1 shared J. Whittaker· 1 shared K. Carr· 1 shared K. E. Hage· 1 shared L. Whittaker· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

B. Dhayalan

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2 papers

Recent·Most cited

Stabilization of a Protein by a Single Halogen-Based Aromatic Amplifier

K. E. Hage, N. B. Phillips, Y.-S. Chen, B. Dhayalan, J. Whittaker, K. Carr, L. Whittaker, M. H. Phillips, F. Ismail-Beigi, M. Meuwly, M. A. Weiss

This study demonstrates that halogenation of an aromatic ring in insulin stabilizes the protein and enhances its resistance to fibrillation and biological activity.

bioRxiv · Jul 25, 2022Biochemistry

Age of diabetes onset in the mutant proinsulin syndrome correlates with mutational impairment of protein foldability and stability

B. Dhayalan, Y.-S. Chen, Y. Yang, M. Jarosinski, D. Chatterjee, R. Grabowski, S. Poordian, N. F. B. Phillips, P. Arvan, F. Ismail-Beigi, M. A. Weiss

The paper investigates how mutations at position B18 in proinsulin affect protein foldability and stability, correlating these effects with the age of diabetes onset in mutant proinsulin syndrome.

bioRxiv · Sep 24, 2021 · PreprintBiochemistry