Epithelial organoid supports resident memory CD8 T cell differentiation
M. Ulibarri, Y. Lin, J. R. Ramprashad, G. Han, M. H. Hasan, F. J. Mithila, C. Ma, S. Gopinath, N. Zhang, J. J. Milner, L. Beura
This paper develops a murine vaginal epithelial organoid system that supports CD8 T cell differentiation into resident memory T cells in vitro, showing phenotypic and transcriptional similarity to in vivo TRM.
bioRxiv · Dec 1, 2023Immunology