Author

F. Lesage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:electrophysiology· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

B. Thebaud· 2 shared C. Cyr-Depauw· 2 shared D. P. Cook· 2 shared I. Mizikova· 2 shared S. Feliciangeli· 2 shared A. Jauch· 1 shared A. Vadivel· 1 shared B. C. Vanderhyden· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

B. Thebaud

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mechanistic basis of the dynamic response of TWIK1 ionic selectivity to pH

F. C. Chatelain, N. Gilbert, D. Bichet, A. Jauch, S. Feliciangeli, F. LESAGE, O. Bignucolo

The paper identifies a network of residues responsible for TWIK1 channel's pH-dependent shift in ionic selectivity from K+ to Na+ using MD simulations, mutagenesis, and electrophysiology.

bioRxiv · Nov 9, 2023Biochemistry

Predicting hERG repolarization power at 37°C from recordings at room temperature

B. Ribeiro, M. Alameh, J. Montnach, B. Ollivier, S. Gibaud, S. Feliciangeli, F. Lesage, F. Charpentier, G. Loussouarn, M. De Waard, I. Baro

The paper develops a method to predict hERG repolarization power at 37°C using room temperature recordings to accelerate variant functional characterization.

bioRxiv · Apr 13, 2023Physiology

An Anatomically and Hemodynamically Realistic Simulation Framework for 3D Ultrasound Localization Microscopy

H. Belgharbi, J. Poree, R. Damseh, V. Perrot, P. Delafontaine-Martel, F. Lesage, J. Provost, L. Milecki

This study introduces a 3D ULM simulation framework to quantify how MB concentration and PSF volume affect resolution and acquisition time, finding that higher frequencies improve resolution but require less time.

bioRxiv · Oct 8, 2021 · PreprintBioengineering

Single-cell RNA sequencing-based characterization of resident lung mesenchymal stromal cells in bronchopulmonary dysplasia

I. Mizikova, F. Lesage, C. Cyr-Depauw, D. P. Cook, M. Hurskainen, S. Hanninen, A. Vadivel, P. Bardin, S. Zhong, O. Carpen, B. C. Vanderhyden, B. Thebaud

This study uses scRNA-seq to characterize resident lung mesenchymal stromal cells in normal development and BPD, finding hyperoxia alters their gene expression and identifies Serpinf1 as a stable marker.

bioRxiv · Jun 18, 2021Cell Biology

Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse

M. K. Hurskainen, I. Mizikova, D. P. Cook, C. Cyr-Depauw, F. Lesage, N. Andersson, E. Helle, L. Renesme, R. P. Jankov, M. Heikinheimo, B. Vanderhyden, B. Thebaud

The paper uses scRNA-seq to analyze lung development in mice under normal and hyperoxic conditions, identifying cellular changes linked to bronchopulmonary dysplasia.

bioRxiv · Dec 22, 2019 · PreprintCell Biology