Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
16 papers
Recent·Most cited
D. P. Radin, S. Zhong, R. Cerne, J. Witkin, A. Lippa
This study shows high impact AMPAkines induce Gq-protein mediated calcium release from ER stores in neurons, explaining their toxicity compared to low impact AMPAkines.
bioRxiv · Jan 28, 2024Pharmacology & Toxicology
H. Yan, J. P. Mendieta, X. Zhang, A. P. Marand, Y. Liang, Z. Luo, M. A. A. Minow, H. Jang, X. Li, T. Roule, D. Wagner, X. Tu, Y. Wang, D. Jiang, S. Zhong, , R. J. Schmitz
The paper constructs a single-cell chromatin accessibility atlas in rice and compares it across grass species to study the evolution of cell-type-specific cis-regulatory elements.
bioRxiv · Jan 8, 2024 · PreprintPlant Biology
J. P. Mendieta, X. Tu, H. Yan, X. Zhang, A. P. Marrand, S. Zhong, R. J. Schmitz
This study uses single-cell ATAC-seq to analyze cis-regulatory elements in C4 photosynthesis across grass species, revealing cell-type-specific chromatin accessibility patterns and evolutionary dynamics.
bioRxiv · Jan 5, 2024 · PreprintPlant Biology
Y. Leng, F. Kümmel, M. Zhao, I. Molnar, J. Dolezel, E. Logemann, P. Köchner, P. Xi, S. Yang, M. J. Moscou, J. D. Fiedler, Y. Du, B. Steuernagel, S. Meinhardt, B. J. Steffenson, , S. Zhong
This study identifies Scs6, a barley gene required for susceptibility to the necrotrophic fungus Bipolaris sorokiniana, and shows it is targeted by a non-ribosomal peptide effector.
bioRxiv · Dec 13, 2023 · PreprintPlant Biology
Y. Li, R. Cao, W. Ren, Y. Fu, Y. Hou, S. Zhong, K. Zhanghao, M. Li, P. Xi
This paper introduces a high-speed 3DSIM system using DMD and electro-optic modulators, achieving improved resolution and imaging speed for various biological specimens.
bioRxiv · Dec 4, 2023 · PreprintCell Biology
J. Popow, W. Farnaby, A. Gollner, C. Kofink, G. Fischer, M. Wurm, D. Zollman, A. Wijaya, N. Mischerikow, C. Hasenoehrl, P. Prokofeva, H. Arnhof, S. Arce-Solano, S. Bell, G. Boeck, , A. Ciulli
A single small molecule degrader targets 13 out of 17 prevalent oncogenic KRAS alleles, inhibiting growth of KRAS-driven cancer cell lines and inducing tumour regression in vivo.
bioRxiv · Oct 24, 2023Pharmacology & Toxicology
T. Xu, E. Zhu, C. Zhang, R. Calandrelli, P. Lin, S. Zhong
The paper introduces HiFi-Slides, a high-resolution spatial transcriptomic technique for analyzing tissue cell gradients, gene expression, and cell proximity.
bioRxiv · Jun 12, 2023 · PreprintBioengineering
R. Zhang, S. Pan, S. Zheng, Q. Liao, Z. Jiang, D. Wang, X. Li, A. Hu, X. Li, Y. Zhu, X. Shen, X. Zhang, L. Huang, J. Lei, S. Zhong, , X. Guo
This study identifies N-myristoylation of Rpt2 as a mechanism for proteasome-membrane interaction, showing its role in membrane protein homeostasis and its impact on cellular processes and tumor growth.
bioRxiv · May 12, 2023Biochemistry
N. E. Yelina, E. Frangedakis, Z. Wang, T. B. Schreier, J. Rever, M. Tomaselli, E. Forestier, K. Billakurthi, S. Ren, Y. Bai, J. Stewart-Wood, J. Haseloff, S. Zhong, J. M. Hibberd
The paper investigates chloroplast development regulation in liverwort Marchantia polymorpha, finding that GLK controls chloroplast biogenesis while GATA and SCL have no detectable roles.
bioRxiv · Jan 23, 2023Plant Biology
Y. Ou, M. Liu, K. Zhan, W. Wu, J. Huang, H. Sun, H. Zheng, X. Yu, H. Gong, Z. Han, A. Chen, Y. Liao, Y. Lin, G. Liu, Q. Liu, , S. Zhong
This study develops a high-affinity, specific TCR targeting NY-ESO-1 through engineering and screening, showing efficacy in tumor models and approval for clinical trials.
bioRxiv · Oct 12, 2022 · PreprintImmunology
I. Mizikova, F. Lesage, C. Cyr-Depauw, D. P. Cook, M. Hurskainen, S. Hanninen, A. Vadivel, P. Bardin, S. Zhong, O. Carpen, B. C. Vanderhyden, B. Thebaud
This study uses scRNA-seq to characterize resident lung mesenchymal stromal cells in normal development and BPD, finding hyperoxia alters their gene expression and identifies Serpinf1 as a stable marker.
bioRxiv · Jun 18, 2021Cell Biology
X. Wang, X. Wang, S. Sun, X. Tu, K. Lin, L. Qin, X. Wang, G. Li, S. Zhong, P. Li
This study identifies novel regulatory modules involving ZmBEH1 and ZmBZR1 that control leaf angle in maize, offering new gene editing targets for improving plant architecture.
bioRxiv · Feb 2, 2021 · PreprintPlant Biology
S. Zhong, H. Li, Y. Wang, Y. Wang, G. Ji, H. Li, S. Zhang, Z. Liu
This study identifies Bmp8a as a positive regulator of antiviral immunity, showing its role in enhancing type I IFN production and reducing viral load in zebrafish.
bioRxiv · Aug 9, 2020 · PreprintImmunology
A. Jiang, Z. Guo, J. Pan, Y. Zhuang, D. Zuo, C. Hao, Z. Gao, P. Xin, J. Chu, S. Zhong, L. Li
The paper identifies a PIF1-MIR408-PLC repression cascade that links light-induced PIF1 degradation to hormonal changes, regulating seed germination in Arabidopsis.
bioRxiv · Jul 20, 2020Plant Biology
Z. Qu, W. C. Yiu, H. Y. Yip, W. Nong, C. W. C. Yu, I. H. T. Lee, A. Y. P. Wong, N. W. Y. Wong, F. K. M. Cheung, T. F. Chan, K. F. Lau, S. Zhong, K. H. Chu, S. S. Tobe, D. E. K. Ferrier, , J. H. L. Hui
The paper investigates a microRNA cluster in Drosophila leg development, showing that clustering integrates evolutionary constraints on expression and target affinities.
bioRxiv · Feb 28, 2020Evolutionary Biology
B. Wu, Y. Ma, S. Zhong, J. Ge, S. Jiang, Y. Zhang, H. Xu
This study evaluates the prognostic role of c-Met overexpression in high-grade glioma through meta-analysis and finds it correlates with poor progression-free survival but not overall survival.
bioRxiv · Jul 8, 2019 · PreprintCancer Biology