Author

F. P. Lemaigre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Loriot· 3 shared C. Gerard· 2 shared K. Konobrocka· 2 shared M. Di-Luoffo· 2 shared M. Komuta· 2 shared S. Cordi· 2 shared S. Pirenne· 2 shared C. Hubert· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

A. Loriot

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Author profile →

3 papers

Recent·Most cited

Spatial transcriptomics profiling of gallbladder adenocarcinoma: a detailed two-case study of progression from precursor lesions to cancer

S. Pirenne, F. Manzano-Nunez, A. Loriot, S. Cordi, L. Desmet, S. Aydin, C. Hubert, S. Toffoli, N. Limaye, C. Sempoux, M. Komuta, L. Gatto, F. P. Lemaigre

This study uses spatial transcriptomics to analyze two gallbladder cancer patients, showing distinct progression paths and the role of SEMA4A repression in tumor development.

bioRxiv · Feb 27, 2024Cancer Biology

A novel mouse model of cholangiocarcinoma uncovers a role for a SOX17-Tensin 4 pathway in tumor progression

M. Di-Luoffo, S. Pirenne, T. Saandi, A. Loriot, C. Gerard, N. Dauguet, F. Lamoline, K. Konobrocka, V. De Greef, M. Komuta, P. Jacquemin, F. P. Lemaigre

This study develops a mouse model of intrahepatic cholangiocarcinoma (iCCA) and identifies a SOX17-Tensin 4 pathway that promotes tumor progression.

bioRxiv · Dec 31, 2019 · PreprintCancer Biology

Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma

C. Gerard, M. Di-Luoffo, L. Gonay, S. Caruso, G. Couchy, A. Loriot, J. Tao, K. Konobrocka, S. Cordi, S. P. Monga, E. Hanert, J. Zucman-Rossi, F. P. Lemaigre

The paper identifies and models a gene regulatory network linking LIN28B-dependent dedifferentiation with CTNNB1 dysfunction in HCC, predicting drug response and cell state dynamics.

bioRxiv · Jun 15, 2018Cancer Biology