Author

F. Speelman-Rooms

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. R. Voet· 1 shared A. Shemy· 1 shared B. Ghesquiere· 1 shared F. Sneyers· 1 shared G. Bultynck· 1 shared G. Eelen· 1 shared K. Welkenhuyzen· 1 shared M. D. Bootman· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. R. Voet

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1 paper

Recent·Most cited

Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing Mcl-1-addicted cancer cells

F. Sneyers, M. Kerkhofs, K. Welkenhuyzen, F. Speelman-Rooms, A. Shemy, A. R. Voet, G. Eelen, M. Dewerchin, S. Tait, B. Ghesquiere, M. D. Bootman, G. Bultynck

This paper shows that BAPTAi inhibits PFKFB3, reducing mTORC1-driven Mcl-1 translation and killing Mcl-1-dependent cancer cells, independent of Ca2+ signaling.

bioRxiv · Oct 31, 2022 · PreprintCell Biology