Cleavage of the Hippo kinases and programmed cell death in murine macrophages exposed to sterile stimuli and bacterial pathogens
Sydney M. Quagliato, Matthew Gulker, Ryan Mirhosiny, Lucas Meints, Brendyn M. St. Louis, Yu-Ting Su, Fangyuan Sun, Yuan He, Pei‐Chung Lee
This study shows that MST1/2 cleavage in macrophages mediates programmed cell death in response to sterile stimuli and bacterial pathogens, with distinct pathways depending on inflammasome activation.
Journal of Biological Chemistry · Nov 7, 2025Peer-reviewedMicrobiology