Author

Pei‐Chung Lee

Wayne State UniversityORCID 0000-0002-8352-7152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Brendyn M. St. LouisiD· 2 shared Fangyuan Sun· 1 shared Haidong GuiD· 1 shared Lucas Meints· 1 shared Matthew Gulker· 1 shared Ryan Mirhosiny· 1 shared Sydney M. QuagliatoiD· 1 shared Udayan GuhaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Brendyn M. St. LouisORCID

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2 papers

Recent·Most cited

Multifaceted regulations of HSV-1 ICP0 on the Anti-Viral Restrictions Imposed by the Host Hippo Kinases Reprogramming

Brendyn M. St. Louis, Udayan Guha, Pei‐Chung Lee, Haidong Gu

This study investigates how HSV-1 interacts with the host Hippo kinase pathway, showing that viral proteins like ICP0 counteract host defenses by modulating MST1/2 cleavage and apoptosis during infection.

bioRxiv · Jun 11, 2026 · PreprintMicrobiology

Cleavage of the Hippo kinases and programmed cell death in murine macrophages exposed to sterile stimuli and bacterial pathogens

Sydney M. Quagliato, Matthew Gulker, Ryan Mirhosiny, Lucas Meints, Brendyn M. St. Louis, Yu-Ting Su, Fangyuan Sun, Yuan He, Pei‐Chung Lee

This study shows that MST1/2 cleavage in macrophages mediates programmed cell death in response to sterile stimuli and bacterial pathogens, with distinct pathways depending on inflammasome activation.

Journal of Biological Chemistry · Nov 7, 2025Peer-reviewedMicrobiology