Cell BiologyKidney InternationalPeer-reviewed
ROCK1 activates mitochondrial fission leading to oxidative stress and muscle atrophy
Meijun Si, Jihong Chen, Rizhen Yu…·Zhaoyong Hu
This study identifies ROCK1 activation as a driver of mitochondrial fission and oxidative stress in CKD-induced muscle wasting, showing pharmacological inhibition of ROCK1 can alleviate these effects.
12 citations