A unified genetic perturbation language for human cellular programming
Austin Hartman, Oliver Takacsi-Nagy, Courtney Kernick, Nicole E. Theberath, Johnathan Lu, Lujing Wu, Michelle Mantilla, Siddhesh Mittra, Alison K. McClellan, Nicole Johnson, Lina Mohamad, Lesly Castillo-Colin, Farzad Hoque, Alexander Eapen, Andy Y. Chen, , Theodore L. Roth
CRISPR-All enables genome-scale, combinatorial genetic perturbations in human cells, revealing additive functional improvements through multiplexed modifications.
bioRxiv · Nov 20, 2025 · PreprintGenetics